Pesquisa sobre: MFN=57742 
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Descritor Inglês:   Diterpene Alkaloids 
Descritor Espanhol:   Alcaloides Diterpénicos 
Descritor Português:   Alcaloides Diterpenos 
Sinônimos Inglês:   Alkaloids, Diterpene  
Categoria:   D02.455.849.291.184
Definição Inglês:   Alkaloids derived from diterpenes (e.g., KAURANES; CLERODANES) often containing the nitrogen bridge structures. These alkaloids may be divided into C18-, C19-, C20- and bis-diterpene types depending on the number of carbon atoms in their central framework. They are found most often in RANUNCULACEAE (e.g., ACONITUM and DELPHINIUM) and may possess analgesic, antiarrhythmic and anti-inflammatory activities. Some are cardiotoxic by blocking L-TYPE CALCIUM CHANNELS. 
Nota Histórica Inglês:   2019 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número do Registro:   57742 
Identificador Único:   D000077743 

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