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Descritor Inglês:   Thymalfasin 
Descritor Espanhol:   Timalfasina 
Descritor Português:   Timalfasina 
Sinônimos Inglês:   Thymosin alpha(1)
Thymosin alpha1
alpha1 Thymosin
Categoria:   D06.472.910.850.500
Definição Inglês:   A thymus hormone polypeptide found in thymosin fraction 5 (a crude thymus gland extract) but now produced by synthesis. It is used alone or with interferon as an immunomodulator for the treatment of CHRONIC HEPATITIS B and HEPATITIS C. Thymalfasin is also used for the treatment of chemotherapy-induced immunosuppression, and to enhance the efficacy of influenza and hepatitis B vaccines in immunocompromised patients. 
Ação Farmacológica:   Adjuvants, Immunologic
Nota Histórica Inglês:   2019 (1980) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número do Registro:   57703 
Identificador Único:   D000077596 

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