Pesquisa sobre: MFN=57613 
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Descritor Inglês:   Agammaglobulinaemia Tyrosine Kinase 
Descritor Espanhol:   Agammaglobulinemia Tirosina Quinasa 
Descritor Português:   Tirosina Quinase da Agamaglobulinemia 
Sinônimos Inglês:   B Cell Progenitor Kinase
Bruton Tyrosine Kinase
Bruton's Tyrosine Kinase
Brutons Tyrosine Kinase
Kinase, Agammaglobulinaemia Tyrosine
Kinase, Bruton's Tyrosine
Tyrosine Kinase, Agammaglobulinaemia
Tyrosine Kinase, Bruton's  
Categoria:   D08.811.913.696.620.682.725.025
Definição Inglês:   A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA. 
Nota Histórica Inglês:   2019 (1993) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57613 
Identificador Único:   D000077329 

Ocorrência na BVS:
 
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