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Descritor Inglês:   Rimonabant 
Descritor Espanhol:   Rimonabant 
Descritor Português:   Rimonabanto 
Sinônimos Inglês:   Acomplia
N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride
Rimonabant Hydrochloride
SR 141716
SR 141716A
Categoria:   D03.383.129.539.888
Definição Inglês:   A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY. 
Ação Farmacológica:   Anti-Obesity Agents
Cannabinoid Receptor Antagonists
Nota Histórica Inglês:   2019 (1994) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   57586 
Identificador Único:   D000077285 

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