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Descritor Inglês:   Survivin 
Descritor Espanhol:   Survivin 
Descritor Português:   Survivina 
Sinônimos Inglês:   BIRC5 Protein
Baculoviral IAP Repeat containing Protein 5
Baculoviral IAP Repeat-containing Protein 5  
Categoria:   D12.644.360.075.437.625
Definição Inglês:   An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA. 
Nota Histórica Inglês:   2019 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57504 
Identificador Único:   D000077022 

Ocorrência na BVS: