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Descritor Inglês:   Abuse-Deterrent Formulations 
Descritor Espanhol:   Formulaciones Disuasorias del Abuso 
Descritor Português:   Formulações de Dissuasão de Abuso 
Sinônimos Inglês:   Abuse Deterrent Formulations
Abuse-Deterrent Formulation
Formulation, Abuse-Deterrent
Formulations, Abuse-Deterrent  
Categoria:   D26.255.075
Definição Inglês:   Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods. 
Relacionados Inglês:   Drug Compounding
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AE adverse effects CL classification
EC economics ES ethics
HI history IS instrumentation
MT methods MO mortality
NU nursing PX psychology
ST standards SN statistics & numerical data
TD trends UT utilization
VE veterinary  
Número do Registro:   57149 
Identificador Único:   D000075162 

Ocorrência na BVS: