Pesquisa sobre: MFN=57095 
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Descritor Inglês:   CCCTC-Binding Factor 
Descritor Espanhol:   Factor de Unión a CCCTC 
Descritor Português:   Fator de Ligação a CCCTC 
Sinônimos Inglês:   CTCF Protein
DNA-Binding Protein CTCF
CCCTC Binding Factor
CTCF, DNA-Binding Protein
DNA Binding Protein CTCF  
Categoria:   D12.776.157.687.157
Definição Inglês:   A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING. 
Nota Histórica Inglês:   2018 (1998) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57095 
Identificador Único:   D000076246 

Ocorrência na BVS: