Pesquisa sobre: MFN=57034 
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Descritor Inglês:   c-Mer Tyrosine Kinase 
Descritor Espanhol:   Tirosina Quinasa c-Mer 
Descritor Português:   c-Mer Tirosina Quinase 
Sinônimos Inglês:   MERTK
c-Mer Proto-Oncogene Tyrosine Kinase
Kinase, c-Mer Tyrosine
Tyrosine Kinase, c-Mer
c Mer Proto Oncogene Tyrosine Kinase
c Mer Tyrosine Kinase  
Categoria:   D08.811.913.696.620.682.725.400.003
Definição Inglês:   A receptor tyrosine kinase that transduces signals from EXTRACELLULAR MATRIX to the CYTOPLASM by binding ligands such as GALECTIN 3. It regulates many physiologic processes that include cell survival, migration, differentiation, and PHAGOCYTOSIS of apoptotic cells and ROD PHOTORECEPTORS in the RETINAL PIGMENT EPITHELIUM. Mutations in the MERTK gene are associated with type 38 RETINITIS PIGMENTOSA; it also plays a critical role as an inhibitor of TOLL-LIKE RECEPTORS signaling. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Número do Registro:   57034 
Identificador Único:   D000076202 

Ocorrência na BVS: