Pesquisa sobre: MFN=57022 
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Descritor Inglês:   Dual Oxidases 
Descritor Espanhol:   Oxidasas Duales 
Descritor Português:   Oxidases Duais 
Sinônimos Inglês:   DUOX1
Dual Oxidase 1
Dual Oxidase 2
Duox Proteins
NADPH Thyroid Oxidase 2
Thyroid Oxidase 2
Oxidase 1, Dual
Oxidase 2, Dual
Oxidase 2, Thyroid
Oxidases, Dual
Proteins, Duox  
Categoria:   D08.811.682.608.575.500
Definição Inglês:   NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57022 
Identificador Único:   D000074623 

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