Pesquisa sobre: MFN=57006 
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Descritor Inglês:   Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein 
Descritor Espanhol:   Proteína 1 de la Translocación del Linfoma del Tejido Linfático Asociado a Mucosas 
Descritor Português:   Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa 
Sinônimos Inglês:   MALT-1 Protein
MALT1 Paracaspase
MALT1 Protein
MALT 1 Protein
Mucosa Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
Paracaspase, MALT1  
Categoria:   D08.811.277.656.262.500.126.775
Definição Inglês:   A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57006 
Identificador Único:   D000074884 

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