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Descritor Inglês:   Type VII Secretion Systems 
Descritor Espanhol:   Sistemas de Secreción Tipo VII 
Descritor Português:   Sistemas de Secreção Tipo VII 
Sinônimos Inglês:   ESX Secretion Systems
Secretion Systems, ESX
Secretion Systems, Type 7
Secretion Systems, Type VII
T7SS Secretion System
Type 7 Secretion Systems
Secretion System, T7SS
System, T7SS Secretion
Systems, ESX Secretion  
Categoria:   D05.500.890.500.992
Definição Inglês:   Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane. 
Nota Histórica Inglês:   2016 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   55951 
Identificador Único:   D000069377 

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