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Descritor Inglês:   Type I Secretion Systems 
Descritor Espanhol:   Sistemas de Secreción Tipo I 
Descritor Português:   Sistemas de Secreção Tipo I 
Sinônimos Inglês:   Bacterial Secretion Systems, Type I
T1SS Secretion System
Type 1 Secretion System
Type 1 Secretion Systems
Type I Secretion System
Secretion System, T1SS
System, T1SS Secretion  
Categoria:   D05.500.890.500.500
Definição Inglês:   Gram-negative bacterial secretion systems which translocate effectors in a single step across the inner and outer membranes. The one-step secretion is carried out by a channel that passes from the CYTOPLASM, through the inner membrane, PERIPLASMIC SPACE, and outer membrane, to the EXTRACELLULAR SPACE. The specificity of type I secretions systems are determined by the specificity of the three subcomponents forming the channel - an ATP transporter (ATP-BINDING CASSETTE TRANSPORTERS); a membrane fusion protein (MEMBRANE FUSION PROTEINS); and an outer membrane protein (BACTERIAL OUTER MEMBRANE PROTEINS.) 
Nota Histórica Inglês:   2016 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   55945 
Identificador Único:   D000069177 

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