Search on: SUBACUTE SCLEROSING PANENCEPHALITIS 
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Descriptor English:   Subacute Sclerosing Panencephalitis 
Descriptor Spanish:   Panencefalitis Esclerosante Subaguda 
Descriptor Portuguese:   Panencefalite Esclerosante Subaguda 
Synonyms English:   Encephaltis, Inclusion Body, Measles
Inclusion Body Encephalitis, Measles
Leukoencephalitis, Van Bogaert's
Sclerosing Leukoencephalitis, Subacute
Sclerosing Panencephalitis, Subacute
Leukoencephalitides, Subacute Sclerosing
Leukoencephalitis, Van Bogaert
Leukoencephalitis, Van Bogaerts
Panencephalitides, Subacute Sclerosing
Sclerosing Leukoencephalitides, Subacute
Sclerosing Panencephalitides, Subacute
Subacute Sclerosing Leukoencephalitides
Subacute Sclerosing Leukoencephalitis
Subacute Sclerosing Panencephalitides
Van Bogaert Leukoencephalitis
Van Bogaerts Leukoencephalitis
Van Bogaert's Leukoencephalitis
Leukoencephalitis, Subacute Sclerosing
Panencephalitis, Subacute Sclerosing
SSPE
Measles Inclusion Body Encephalitis  
Tree Number:   C02.182.525.600
C02.290.700
C02.782.580.600.500.500.800
C02.839.862
C10.228.140.430.520.750.600
C10.228.228.245.340.600
C10.228.228.399.750.600
Definition English:   A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8) 
History Note English:   71; VAN BOGAERT'S LEUKOENCEPHALITIS was see under SUBACUTE SCLEROSING PANENCEPHALITIS 1971-78; was see under CEREBRAL SCLEROSIS, DIFFUSE 1963-70 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
TM transmission UR urine
VE veterinary VI virology
Record Number:   13732 
Unique Identifier:   D013344 

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