Search on: SCLEROMYXEDEMA 
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Descriptor English:   Scleromyxedema 
Descriptor Spanish:   Escleromixedema 
Descriptor Portuguese:   Escleromixedema 
Synonyms English:   Lichen Myxedematosus
Mucinosis, Papular
Myxedematosus, Lichen
Papular Mucinosis  
Tree Number:   C17.300.550.875
Definition English:   A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda. 
See Related English:   Myxedema
 
History Note English:   2007 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   52148 
Unique Identifier:   D053718 

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