Search on: RETROGRADE DEGENERATION 
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Descriptor English:   Retrograde Degeneration 
Descriptor Spanish:   Degeneración Retrógrada 
Descriptor Portuguese:   Degeneração Retrógrada 
Synonyms English:   Axonal Reaction
Trans-Synaptic Degeneration
Axon Reactions
Axonal Reactions
Degeneration, Nissl
Degeneration, Retrograde
Degeneration, Trans-Synaptic
Degeneration, Transneuronal Retrograde
Degenerations, Retrograde
Degenerations, Trans-Synaptic
Degenerations, Transneuronal Retrograde
Reaction, Axon
Reaction, Axonal
Reactions, Axon
Reactions, Axonal
Retrograde Degenerations
Retrograde Degenerations, Transneuronal
Trans Synaptic Degeneration
Trans-Synaptic Degenerations
Transneuronal Retrograde Degeneration
Transneuronal Retrograde Degenerations
Axon Reaction
Nissl Degeneration
Retrograde Degeneration, Transneuronal  
Tree Number:   C23.550.737.500
Definition English:   Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons. 
History Note English:   91(75); was see under NERVE DEGENERATION 1975-90; NISSL DEGENERATION was see NERVE DEGENERATION 1997, was heading 1975-96 (see under NERVE DEGENERATION 1975-90) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   12599 
Unique Identifier:   D012183 

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