Search on: POLYMYOSITIS 
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Descriptor English:   Polymyositis 
Descriptor Spanish:   Polimiositis 
Descriptor Portuguese:   Polimiosite 
Synonyms English:   Idiopathic Polymyositides
Idiopathic Polymyositis
Multiple Myositis
Myositides, Multiple
Myositis, Multiple
Ossificans, Polymyositis
Polymyositides
Polymyositides, Idiopathic
Polymyositis Ossificans
Polymyositis, Idiopathic  
Tree Number:   C05.651.594.819
C10.668.491.562.575
Definition English:   Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9) 
History Note English:   93 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   30612 
Unique Identifier:   D017285 

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