Descriptors Found: 1
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Descriptor English:   Pick Disease of the Brain 
Descriptor Spanish:   Enfermedad de Pick 
Descriptor Portuguese:   Doença de Pick 
Synonyms English:   Atrophies, Lobar (Brain)
Atrophy, Lobar (Brain)
Brain Atrophy, Circumscribed Lobar
Circumscribed Lobar Atrophy of the Brain
Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
Disease, Pick
Disease, Pick's
Lobar Atrophies (Brain)
Lobar Atrophy (Brain)
Lobar Atrophy Of Brain
Lobar Atrophy of the Brain
Pick Disease
Pick Disease Of Brain
Pick's Disease
Picks Disease
Picks Disease of Brain  
Tree Number:   C10.228.140.380.266.299.500
Definition English:   A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9) 
History Note English:   2000; for PICKS DISEASE OF BRAIN use DEMENTIA 1992-1999 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DG diagnostic imaging DH diet therapy
DT drug therapy EC economics
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RH rehabilitation SU surgery
TH therapy UR urine
VI virology  
Record Number:   34272 
Unique Identifier:   D020774 

Occurrence in VHL: