Search on: PARANEOPLASTIC CEREBELLAR DEGENERATION 
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Descriptor English:   Paraneoplastic Cerebellar Degeneration 
Descriptor Spanish:   Degeneración Cerebelosa Paraneoplásica 
Descriptor Portuguese:   Degeneração Paraneoplásica Cerebelar 
Synonyms English:   Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Cerebellar Syndrome, Paraneoplastic
Paraneoplastic Cerebellar Syndrome
Anti Yo Associated Paraneoplastic Cerebellar Degeneration
Cerebellar Syndromes, Paraneoplastic
Degeneration, Paraneoplastic Cerebellar
Paraneoplastic Cerebellar Degeneration, Anti Yo Associated
Paraneoplastic Cerebellar Syndromes
Cerebellar Degeneration, Paraneoplastic
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated  
Tree Number:   C04.588.614.550.650
C04.730.856.650
C10.228.140.252.620
C10.574.781.700
Definition English:   Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686) 
Indexing Annotation English:   coord with precoord organ/neopl term + histol type
History Note English:   2000 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   34185 
Unique Identifier:   D020362 

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