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Descriptor English:   Paget Disease, Extramammary 
Descriptor Spanish:   Enfermedad de Paget Extramamaria 
Descriptor Portuguese:   Doença de Paget Extramamária 
Synonyms English:   Extra Mammary Paget Disease
Extra Mammary Paget's Disease
Extra-Mammary Paget Disease
Extra-Mammary Paget's Disease
Extra-Mammary Pagets Disease
Extramammary Paget Disease
Extramammary Paget's Disease
Extramammary Pagets Disease
Extramammary, Paget Disease
Paget Disease Extramammary
Paget Disease, Extra Mammary
Paget Disease, Extra-Mammary
Paget's Disease, Extra Mammary
Paget's Disease, Extra-Mammary
Paget's Disease, Extramammary
Pagets Disease, Extra-Mammary
Pagets Disease, Extramammary  
Tree Number:   C04.557.470.200.025.660
Definition English:   A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478) 
Indexing Annotation English:   neoplastic; coordinate with precoordinated organ/neoplasm term
History Note English:   2010(1963) 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SC secondary SU surgery
TH therapy UL ultrastructure
UR urine VE veterinary
VI virology  
Record Number:   31760 
Unique Identifier:   D010145 

Occurrence in VHL: