Search on: MYELOPROLIFERATIVE DISORDERS 
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Descriptor English:   Myeloproliferative Disorders 
Descriptor Spanish:   Trastornos Mieloproliferativos 
Descriptor Portuguese:   Transtornos Mieloproliferativos 
Synonyms English:   Disorder, Myeloproliferative
Disorders, Myeloproliferative
Myeloproliferative Disorder  
Tree Number:   C15.378.190.636
Definition English:   Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE. 
Indexing Annotation English:   myelo- here = bone marrow, not spinal cord; general; prefer specifics
See Related English:   Leukemia
 
History Note English:   70(66) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   9388 
Unique Identifier:   D009196 

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