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Descriptor English:   Glioblastoma 
Descriptor Spanish:   Glioblastoma 
Descriptor Portuguese:   Glioblastoma 
Synonyms English:   Astrocytomas, Grade IV
Giant Cell Glioblastomas
Glioblastoma, Giant Cell
Glioblastomas, Giant Cell
Grade IV Astrocytoma
Grade IV Astrocytomas
Glioblastoma Multiforme
Astrocytoma, Grade IV
Giant Cell Glioblastoma  
Tree Number:   C04.557.465.625.600.380.080.335
Definition English:   A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. 
Indexing Annotation English:   coord IM with probably precoord CNS/neopl term + site (IM); for GLIOBLASTOMA WITH SARCOMATOUS COMPONENT see GLIOSARCOMA; for GLIOBLASTOMA, RETINAL see RETINOBLASTOMA
History Note English:   94; was GLIOBLASTOMA MULTIFORME 1963-93; GLIOBLASTOMA was see ASTROCYTOMA 1993 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SC secondary SE secretion
SU surgery TH therapy
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   31846 
Unique Identifier:   D005909 

Occurrence in VHL: