Search on: ENCEPHALOMALACIA 
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Descriptor English:   Encephalomalacia 
Descriptor Spanish:   Encefalomalacia 
Descriptor Portuguese:   Encefalomalacia 
Synonyms English:   Cerebromalacia
Cerebromalacias
Encephalomalacia, Multicystic
Encephalomalacias
Encephalomalacias, Multicystic
Multicystic Encephalomalacia
Multicystic Encephalomalacias  
Tree Number:   C10.228.140.461
Definition English:   Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75) 
History Note English:   1966(1964) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   4758 
Unique Identifier:   D004678 

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