Search on: ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE 
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Descriptor English:   Anti-Glomerular Basement Membrane Disease 
Descriptor Spanish:   Enfermedad por Anticuerpos Antimembrana Basal Glomerular 
Descriptor Portuguese:   Doença Antimembrana Basal Glomerular 
Synonyms English:   Anti GBM Disease
Anti Glomerular Basement Membrane Disease
Anti-GBM Disease
Goodpasture Syndrome
Goodpasture's Syndrome
Goodpastures Syndrome
Lung Purpura with Nephritis
Syndrome, Goodpasture
Syndrome, Goodpasture's  
Tree Number:   C08.381.483.156
C12.777.419.570.363.304
C13.351.968.419.570.363.304
C20.111.190
Definition English:   An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis. 
See Related English:   Glomerular Basement Membrane
 
History Note English:   1998 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   33358 
Unique Identifier:   D019867 

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