Search on: TISSUE PLASMINOGEN ACTIVATOR 
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Descriptor English:   Tissue Plasminogen Activator 
Descriptor Spanish:   Activador de Tejido Plasminógeno 
Descriptor Portuguese:   Ativador de Plasminogênio Tecidual 
Synonyms English:   Actilyse
Activase
Alteplase
Lysatec rt PA
Lysatec rt-PA
Lysatec rtPA
Plasminogen Activator, Tissue
Plasminogen Activator, Tissue Type
Plasminogen Activator, Tissue-Type
T Plasminogen Activator
T-Plasminogen Activator
TTPA
Tisokinase
Tissue Activator D 44
Tissue Activator D-44
Tissue Type Plasminogen Activator
Tissue-Type Plasminogen Activator  
Tree Number:   D08.811.277.656.300.760.875
D08.811.277.656.959.350.875
D12.776.124.125.662.768
D23.119.970
Definition English:   A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases. 
Pharmacological Action:   Fibrinolytic Agents
 
History Note English:   98(86) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   30438 
Unique Identifier:   D010959 

Occurrence in VHL:
 
LILACS    
MEDLINE    
BDENF    
PAHO    
WHOLIS    
IBECS    

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