Search on: THYMALFASIN 
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Descriptor English:   Thymalfasin 
Descriptor Spanish:   Timalfasina 
Descriptor Portuguese:   Timalfasina 
Synonyms English:   Thymosin alpha(1)
Thymosin alpha1
Zadaxin
alpha1 Thymosin
alpha1-Thymosin  
Tree Number:   D06.472.910.850.500
D12.644.548.869.500
D12.776.922.500
Definition English:   A thymus hormone polypeptide found in thymosin fraction 5 (a crude thymus gland extract) but now produced by synthesis. It is used alone or with interferon as an immunomodulator for the treatment of CHRONIC HEPATITIS B and HEPATITIS C. Thymalfasin is also used for the treatment of chemotherapy-induced immunosuppression, and to enhance the efficacy of influenza and hepatitis B vaccines in immunocompromised patients. 
Pharmacological Action:   Adjuvants, Immunologic
 
History Note English:   2019 (1980) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   57703 
Unique Identifier:   D000077596 

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