Search on: ENDOCRINE DISRUPTORS 
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Descriptor English:   Endocrine Disruptors 
Descriptor Spanish:   Disruptores Endocrinos 
Descriptor Portuguese:   Disruptores Endócrinos 
Synonyms English:   Chemicals, Endocrine Disrupting
Disruptor Effect, Endocrine
Disruptor Effects, Endocrine
Disruptors, Endocrine
Effect, Endocrine Disruptor
Effects, Endocrine Disruptor
Endocrine Disrupting Chemicals
Endocrine Disruptor Effect
Endocrine Disruptor Effects  
Tree Number:   D27.505.696.353
D27.888.141
Definition English:   Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism. 
Indexing Annotation English:   note entry term ENDOCRINE DISRUPTOR EFFECT: use only for the endocrine disruptor effect of a chemical substance
See Related English:   Hormones, Hormone Substitutes, and Hormone Antagonists
 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   51206 
Unique Identifier:   D052244 

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