Search on: DONEPEZIL 
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Descriptor English:   Donepezil 
Descriptor Spanish:   Donepezilo 
Descriptor Portuguese:   Donepezila 
Synonyms English:   1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
Donepezil Hydrochloride
Donepezilium Oxalate Trihydrate
E 2020
Tree Number:   D02.455.426.559.847.486.487.280
Definition English:   An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE. 
Pharmacological Action:   Cholinesterase Inhibitors
Nootropic Agents
History Note English:   2019 (1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   57568 
Unique Identifier:   D000077265 

Occurrence in VHL: