Search on: ALZHEIMER DISEASE 
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Descriptor English:   Alzheimer Disease 
Descriptor Spanish:   Enfermedad de Alzheimer 
Descriptor Portuguese:   Doença de Alzheimer 
Synonyms English:   Acute Confusional Senile Dementia
Alzheimer Dementia
Alzheimer Dementias
Alzheimer Disease, Early Onset
Alzheimer Disease, Familial (FAD)
Alzheimer Disease, Late Onset
Alzheimer Diseases, Familial (FAD)
Alzheimer Sclerosis
Alzheimer Syndrome
Alzheimer Type Dementia
Alzheimer Type Dementia (ATD)
Alzheimer Type Senile Dementia
Alzheimer's Disease
Alzheimer's Disease, Focal Onset
Alzheimer-Type Dementia (ATD)
Dementia, Alzheimer
Dementia, Alzheimer Type
Dementia, Alzheimer-Type (ATD)
Dementia, Presenile
Dementia, Primary Senile Degenerative
Dementia, Senile
Dementias, Alzheimer
Early Onset Alzheimer Disease
Familial Alzheimer Disease (FAD)
Familial Alzheimer Diseases (FAD)
Focal Onset Alzheimer's Disease
Late Onset Alzheimer Disease
Presenile Alzheimer Dementia
Presenile Dementia
Primary Senile Degenerative Dementia
Sclerosis, Alzheimer
Senile Dementia
Senile Dementia, Acute Confusional
Senile Dementia, Alzheimer Type  
Tree Number:   C10.228.140.380.100
C10.574.945.249
F03.615.400.100
Definition English:   A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) 
See Related English:   Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Aphasia, Primary Progressive
Cerebral Amyloid Angiopathy
Kluver-Bucy Syndrome
Neurofilament Proteins
tau Proteins
 
History Note English:   1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   545 
Unique Identifier:   D000544 

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